PSYCHIATRY MCQs pdf free download. Q-1 Olanzapine is known to block D2 dopamine receptors. What other type of receptor does it mainly act on?
B. Acetylcholine receptors
C. Serotonin receptors
D. D1 dopamine receptors
E. H1 histamine receptors
Olanzapine, like other atypical antipsychotics, is known to block serotonin receptors (especially the 5-HT2 subtype) as well as D2 dopamine receptors
Atypical antipsychotics should now be used first-line in patients with schizophrenia, according to 2005 NICE guidelines. The main advantage of the atypical agents is a significant reduction in extra-pyramidal side-effects.
Adverse effects of atypical antipsychotics
• weight gain
• clozapine is associated with agranulocytosis (see below)
The Medicines and Healthcare products Regulatory Agency has issued specific warnings when antipsychotics are used in elderly patients:
• increased risk of stroke
• increased risk of venous thromboembolism
Examples of atypical antipsychotics
PSYCHIATRY MCQs pdf free download
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